Cell Death Mechanisms in Multiple System Atrophy
نویسندگان
چکیده
منابع مشابه
Causes of Death in Chinese Patients with Multiple System Atrophy
The objective of this study was to explore the causes of death in Chinese patients with multiple system atrophy (MSA) as well as differences in the cause of death according to sex, subtype, disease onset, and whether the disease was accompanied by nocturnal stridor. A total of 131 MSA patients were enrolled and followed up once every year until their deaths. Clinical information was collected b...
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Sir, we read with great interest the article by Schwarzacher et al. (2011) describing the neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in multiple system atrophy and spinocerebellar ataxia 3 (SCA3). In this study, the authors provide a thorough analysis of the pre-Bötzinger complex and demonstrate that somatostatin and neurokinin 1 receptor expressing n...
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Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial cytoplasmic inclusions. p25α is a stimulator of α-synuclein aggregation, and coexpression of α-synuclein and p25α in the oligodendroglial OLN-t40-A...
متن کاملMultiple system atrophy.
Multiple system atrophy (MSA) is an adult-onset sporadic progressive neurodegenerative disorder of unknown etiology. It is clinically characterized by the variable combination of autonomic failure, parkinsonism, cerebellar ataxia, and pyramidal signs. The present review summarizes up-to-date knowledge on the clinical diagnosis and molecular pathology of MSA. We also review the role of additiona...
متن کاملMultiple system atrophy.
Multiple system atrophy is a neurological disorder that has gone unrecognized for too long due to its involvement across multiple regions of the central nervous system. This disorder is finally being unveiled through increased reporting in the scientific literature. Further research will enhance our understanding of this disease and lead to more effective treatment regimens as well as an improv...
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ژورنال
عنوان ژورنال: Journal of Neuropathology and Experimental Neurology
سال: 1998
ISSN: 0022-3069
DOI: 10.1097/00005072-199809000-00002